Sofia joins the lab!

  • Posted on: 17 March 2021
  • By: sglab

Sofia Esteban Serna joins our lab!

Sofia is a new Wellcome Trust iCM PhD student in our lab and her project involves understanding the role of RNA-binding proteins in tight regulation of gene expression.

When some genes are expressed at too high levels it can be toxic to the cell. We found a mechanisn that involves RNA-binding proteins that suppresses this overshooting and keeps tight control of expression of some stress-responsive genes.

Sofia's goal will be to dissect this mechanism and understand how it contributes to stress adaptation.

Our Hfq CLASH paper got accepted for publication in eLIFE!

  • Posted on: 30 April 2020
  • By: sglab

My former PhD student Ira Iosub spent about four years working on a project to identify Hfq-mediated sRNA-target interactions.

Her reasearch has unearthed a plethora of novel sRNA-mRNA interactions as well as many sRNA-sRNA interactions that potentiall connect many different metabolic pathways.

Consistent with recent work from Hannah Margalit's lab, we found that sRNA-mRNA interactions that are reproducibly detected are more likely to impact steady state levels of their mRNA targets.

This work was done in collaboration with the labs of Jai Tree and Gabriella Viero! 

Niki Christopoulou is awarded a Darwin Trust PhD studentship!

  • Posted on: 8 April 2019
  • By: sglab

Our ERASMUS student Niki was recently awarded a Darwin Trust PhD studentship!
She will be joining the lab for four years, starting October 2019.

Her project involves understanding the role of RNA-binding proteins involved in antibiotic resistance in pathogenic bacteria.

Congratulations Niki!

 

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Granneman lab welcomes Niki Christopoulou

  • Posted on: 1 October 2018
  • By: sglab

Niki Christopoulou will be in our lab for a few months to learn how to genetically manipulate pathogenic bacteria. She got an ERASMUS fellowship for her stay here in Edinburgh. The goal is to also teach her how to do CLIP/CRAC, should there be sufficient time.

Welcome!

UPDATE!!! She recently was awarded a Darwin Trust PhD fellowship to join our lab. Congratulations!

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