Our S. aureus (MRSA) RNA interactome papers (2x!) have been published in Nature Communications!!!

Using CLASH we unearthed large RNA-RNA interaction networks in this pathogenic and antibiotic resistant bacterium.

Together with Jai Tree's group we identified interactions between non-coding RNAs and mRNAs that regulate (1) tolerance of vancomycin, our last-line antibiotic for battling MRSA, and (2) the production of cytolytic toxins that enable MRSA to survive and even thrive in the hostile host environment.

Importantly, this work would NOT have been possible without the tremendous support and contributions of our collaborators:

Ross Fitzgerald

Isabelle Caldelari

Ronan Carroll

Tim Stinear

Benjamin Howden

Ian Monk

and Greg Kudla's lab!