Our Hfq CLASH paper got accepted for publication in eLIFE!
My former PhD student Ira Iosub spent about four years working on a project to identify Hfq-mediated sRNA-target interactions.
Her reasearch has unearthed a plethora of novel sRNA-mRNA interactions as well as many sRNA-sRNA interactions that potentiall connect many different metabolic pathways.
Consistent with recent work from Hannah Margalit's lab, we found that sRNA-mRNA interactions that are reproducibly detected are more likely to impact steady state levels of their mRNA targets.
This work was done in collaboration with the labs of Jai Tree and Gabriella Viero!
This is Ira's third paper and she will be submitting one more paper soon on which she is first author.
Another super successful PhD student!