Our Hfq CLASH paper got accepted for publication in eLIFE!

  • Posted on: 30 April 2020
  • By: sglab

My former PhD student Ira Iosub spent about four years working on a project to identify Hfq-mediated sRNA-target interactions.

Her reasearch has unearthed a plethora of novel sRNA-mRNA interactions as well as many sRNA-sRNA interactions that potentiall connect many different metabolic pathways.

Consistent with recent work from Hannah Margalit's lab, we found that sRNA-mRNA interactions that are reproducibly detected are more likely to impact steady state levels of their mRNA targets.

This work was done in collaboration with the labs of Jai Tree and Gabriella Viero! 

Our kinetic CRAC paper got accepted by JoVe

  • Posted on: 20 January 2020
  • By: sglab

Our JoVe paper describing a detailed protocol for kinetic CRAC (chiCRAC) has been accepted by JoVe!

The work describing the mammalian iCLIP experiments were done by Ross Cordiner who is a post-doc in Torben Heick Jensen's lab.

Congrats! 

 

https://www.jove.com/video/61027/monitoring-protein-rna-interaction-dyna...

Niki Christopoulou is awarded a Darwin Trust PhD studentship!

  • Posted on: 8 April 2019
  • By: sglab

Our ERASMUS student Niki was recently awarded a Darwin Trust PhD studentship!
She will be joining the lab for four years, starting October 2019.

Her project involves understanding the role of RNA-binding proteins involved in antibiotic resistance in pathogenic bacteria.

Congratulations Niki!

 

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Granneman lab welcomes Niki Christopoulou

  • Posted on: 1 October 2018
  • By: sglab

Niki Christopoulou will be in our lab for a few months to learn how to genetically manipulate pathogenic bacteria. She got an ERASMUS fellowship for her stay here in Edinburgh. The goal is to also teach her how to do CLIP/CRAC, should there be sufficient time.

Welcome!

UPDATE!!! She recently was awarded a Darwin Trust PhD fellowship to join our lab. Congratulations!

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Granneman lab welcomes Ivayla and Tove

  • Posted on: 3 September 2018
  • By: sglab

Ivayla is a new post-doc in the lab who will be working on one of the most pathogenic strains we have in the lab. She is an expert in post-transcriptional modification and this is her first venture into microorganisms.

Tove, a Swedish MSc student in Synthetic Biology, will be manipulating yeast to develop new ways of making expression of exogenous genes more efficient in baker’s yeast.

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